Cross-reactivity of steroid hormone immunoassays: clinical significance and two-dimensional molecular similarity prediction

  • Matthew D Krasowski, Denny Drees, Cory S Morris, Jon Maakestad, John L Blau, Sean Ekins
  • BMC Clinical Pathology, July 2014, Springer Science + Business Media
  • DOI: 10.1186/1472-6890-14-33

2D similarity and steroid hormone immunoassays

What is it about?

Using 2D similarity to assess cross reactivity of other compounds with commercial immunoassays.

Why is it important?

2D similarity looks like a useful predictor of cross reactivity with the commercial immunoassays. This may be important for diagnostic and tox labs.

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http://dx.doi.org/10.1186/1472-6890-14-33

The following have contributed to this page: Dr Sean Ekins