What is it about?
Imatinib therapy following debulking surgery can show dramatic effectiveness in giant gastric GISTs with severe peritoneal dissemination.
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Why is it important?
We report the case of a patient with a giant gastric GIST with severe peritoneal dissemination, showing favorable progression control by postoperative imatinib therapy following debulking surgery. This case demonstrated that surgery can possibly play a role even in unresectable GISTs.
Perspectives
Prior to the imatinib era, surgery traditionally played only a palliative role in patients with unresectable GISTs; however, with the introduction of imatinib, it may be necessary to reassess the role of surgery in these cases.
Shuichi Fukuda
Kindai Universiry Nara Hospital
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This page is a summary of: Giant gastric gastrointestinal stromal tumor with severe peritoneal dissemination controlled by imatinib therapy following debulking surgery: a case report, Journal of Medical Case Reports, February 2017, Springer Science + Business Media,
DOI: 10.1186/s13256-017-1215-5.
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