What is it about?

Evaluate the expression of HIF-1α and VEGF in feline mammary carcinomas and analyze their correlations with clinical and pathological factors.

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Why is it important?

This study suggests that the overexpression of HIF-1α may indicate poor prognosis/overall survival rate in cats with FMGCs. Developing compounds that inhibit HIF-1α may be a potential approach to FMGC treatment.

Perspectives

This study provides 1) a direction of drug development for treating feline mammary carcinomas and 2) new prognostic factors to evaluate the prognosis in cat with mammary carcinomas

Dr. Wen-Ta Li
Fishhead Labs LLC

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This page is a summary of: Expression of HIF-1α and VEGF in feline mammary gland carcinomas: association with pathological characteristics and clinical outcomes, BMC Veterinary Research, May 2020, Springer Science + Business Media, DOI: 10.1186/s12917-020-02338-y.
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