What is it about?

Pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis (CP) that requires a high index of clinical suspicion in the patient who presents with a pleural effusion.

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Why is it important?

The diagnosis of PPF in children requires a high index of clinical suspicion and should be considered in the differential diagnosis of massive pleural effusion where pancreatic pathology is present. A high level of pleural fluid amylase and the results from radiological imaging when the patients have symptoms play essential roles in the diagnosis of PPF.


Currently, Magnetic resonance cholangiopancreatigraphy (MRCP) is the imaging modality of choice. Endoscopic therapy and surgery are treatment options for patients who do not respond to conservative therapy.

Dr. Prakarn Tovichien
Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University

Read the Original

This page is a summary of: Pancreaticopleural fistula in a child with chronic pancreatitis harboring compound SPINK1 variants, BMC Gastroenterology, June 2021, Springer Science + Business Media,
DOI: 10.1186/s12876-021-01842-1.
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