What is it about?
The incidence of indeterminate pulmonary nodules has risen constantly over the past few years. Determination of lung nodule malignancy is pivotal, because the early diagnosis of lung cancer could lead to a definitive intervention.
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Why is it important?
Physicians should be aware that size and its change over time remain the most important factors determining nodule management, as stated in the currently used international guidelines, even though these factors should be evaluated in relation to other nodule characteristics, without overlooking the clinical context.
Perspectives
Predictive models that take into account several factors have been proposed as a potential means to overcome the limitations of a size-based assessment of the malignancy risk for indeterminate pulmonary nodules.
Anna Rita Larici
Catholic University of Sacred Heart, Rome, Italy
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This page is a summary of: Lung nodules: size still matters, European Respiratory Review, December 2017, European Respiratory Society (ERS),
DOI: 10.1183/16000617.0025-2017.
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