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There are some circumstances that have demonstrated a negative impact on the natural history of bronchiectasis: certain comorbidities, the presence of chronic bronchial infection by Pseudomonas aeruginosa (PA) and the existence of exacerbations (especially if multiple and/or severe)
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Pseudomonas aeruginosa
infection and exacerbations in bronchiectasis: more questions than answers
, European Respiratory Journal, January 2018, European Respiratory Society (ERS),
DOI: 10.1183/13993003.02497-2017.
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