Oxidative stress biomarkers and asthma characteristics in adults of the EGEA study

What is it about?

Asthma is an oxidative stress-related disease but few studies are available on the associations with asthma characteristics, particularly in adults. The aim of this study is to assess the associations between biomarkers of response or of damage related to oxidative stress and various asthma outcomes. Results showed that biomarkers of response were not associated with any asthma outcomes. 8-isoprostanes level was higher in adults with ever asthma, while Fluorescent oxidation products (FlOPs) level, a global marker of oxidation process, was higher in adults with poor asthma outcomes and poor lung function. Our study suggests 8-isoprostanes and FlOPs as biomarkers of interest for studying oxidative stress-related damage in chronic diseases such as asthma.

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