What is it about?
DLCO and KCO are very dependent on lung volume, so adjusting predicted DLCO and KCO for lung volume is essential. This reviews how to make those adjustments, and recommends how to report DLCO, including the effect of lung volume, Hb, and other factors that effect predicted DLCO
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Why is it important?
Since DLCO and KCO change significantly with lung volume, it is important to adjust predicted values for lung volume to evaluate the lung's ability for gas exchange. Is a low DLCO due to low lung volume or abnormal gas exchange? Does a "normal" KCO reflect normal gas exchange, or very abnormal gas exchange since it should be much "above normal" due to low lung volume?
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This page is a summary of: DLCO: adjust for lung volume, standardised reporting and interpretation, European Respiratory Journal, August 2017, European Respiratory Society (ERS),
DOI: 10.1183/13993003.00940-2017.
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