What is it about?
Nintedanib can be used as a therapeutic intervention in mouse models that exhibit pathology similar to rheumatoid arthritis-associated interstitial lung disease (RA-ILD). This data is also expected to have an impact on patients with RA-ILD.
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Why is it important?
Nintedanib is expected to have an effect on fibroblasts. In this paper, it was shown that nintedanib also acts on epithelial abnormalities, suggesting that it may prevent cancer in the future.
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This page is a summary of: Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model, ERJ Open Research, September 2021, European Respiratory Society (ERS),
DOI: 10.1183/23120541.00345-2021.
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