What is it about?

In multiple pulmonary diseases, CLE has been demonstrated to be an effective and minimally invasive technique that enables the real-time visualization of lesions with a diverse field of view. In a near future, it can be envisaged that a large atlas of CLE images for different pulmonary diseases will be established and can be identified automatically using artificial intelligence; as a result, the role of CLE in facilitating advanced diagnostic capabilities, monitoring, and evaluating the treatment response for patients with pulmonary diseases will be further highlighted. Notably, CLE is solely a component of an integrated management in pulmonary medicine; in order to incorporate the benefits and minimize the deficiencies of every single technique, CLE in conjunction with other technologies should be the preferred strategy.

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Why is it important?

Confocal laser endomicroscopy (CLE) serves as an effective and minimally invasive technique in multiple pulmonary diseases. In the future, a combination of CLE and artificial intelligence has potential to become the main trend.


Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. This article also lead to CLE groups contacting me and ultimately to a greater involvement in CLE research.

Sen Tian

Read the Original

This page is a summary of: The role of confocal laser endomicroscopy in pulmonary medicine, European Respiratory Review, January 2023, European Respiratory Society (ERS),
DOI: 10.1183/16000617.0185-2022.
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