What is it about?
We randomized pregnant women unable to quit smoking during pregnancy to vitamin C (500 mg/day) versus placebo and showed the infants born to the women who received the extra vitamin C had better lung function through 12 months of age.
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Why is it important?
Vitamin C combined with smoking cessation counseling for pregnant smokers may be a safe, inexpensive, and simple intervention to improve the airway function of their offspring through 12 months of age.
Perspectives
I am very excited about our results because vitamin C to pregnant smokers may help improve the trajectory of their infant’s lung function and improve their lifelong respiratory health.
Cindy McEvoy
Oregon Health & Science University
Read the Original
This page is a summary of: Vitamin C to pregnant smokers persistently improves infant airway function to 12 months of age: a randomised trial, European Respiratory Journal, July 2020, European Respiratory Society (ERS),
DOI: 10.1183/13993003.02208-2019.
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Resources
Previous, Vitamin C Study
Vitamin C supplementation for pregnant smoking women and pulmonary function in their newborn infants: a randomized clinical trial
Pulmonary Effects of Maternal Smoking on the Fetus and Child
Pulmonary Effects of Maternal Smoking on the Fetus and Child: Effects on Lung Development, Respiratory Morbidities, and Life Long Lung Health
Vitamin C, DNA Methylation
Vitamin C Prevents Offspring DNA Methylation Changes Associated with Maternal Smoking in Pregnancy
Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP): Rationale, design, and methods of a randomized, controlled trial of vitamin C supplementation in pregnancy for the primary prevention of effects of in utero tobacco smoke exposure on infant lung function and respiratory health
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