What is it about?
We compared the eff i c acy of p irfenidone plus inhaled N acetylcysteine with results for pirfenidone alone for idiopathic pulmonary fibrosis . Combination treatment with inhaled N acetylcysteine and pirfenidone is likely to result in worse outcomes for IPF .
Photo by Ice Tea on Unsplash
Why is it important?
The efficacy and tolerability of combination therapy with an antifibrotic agent and inhaled N-acetylcysteine are unclear. This study th erefore compared the efficacy and safety of combination treatment with pirfenidone and inhaled N-acetylcysteine 352.4mg twice daily with the results for pirfenidone alone for treatment of IPF over a 48 week treatment period
Read the Original
This page is a summary of: Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial, European Respiratory Journal, July 2020, European Respiratory Society (ERS), DOI: 10.1183/13993003.00348-2020.
You can read the full text:
The following have contributed to this page