The clinical significance of oropharyngeal cultures in young children with cystic fibrosis

Oded Breuer, Daan Caudri, Lauren Akesson, Sarath Ranganathan, Stephen M. Stick, André Schultz
  • European Respiratory Journal, April 2018, European Respiratory Society (ERS)
  • DOI: 10.1183/13993003.00238-2018

Oropharyngeal swabs not useful in young children with CF

What is it about?

Oropharyngeal swab cultures in children with cystic fibrosis are not helpful for ruling out lower airway Pseudomonas infection and are not associated with structural lung disease, lung inflammation or admissions for respiratory exacerbations

Why is it important?

Findings from this study do not support the routine use of OPS cultures in ruling out lower airway infections and highlight the need to develop a more robust feasible method for early detection of lower airway P. aeruginosa infection which will help guide treatment and prevent or delay the progression of destructive lung disease in young children.

Perspectives

Oded Breuer (Author)
Telethon Kids Institute

Despite ongoing evidence that oropharyngeal swabs lack sensitivity to detect lower airway P. aeruginosa infection and evidence established by current study that results of these swabs are not associated with disease, oropharyngeal swabs are still widely used to determine treatment in young patients with CF.

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http://dx.doi.org/10.1183/13993003.00238-2018

The following have contributed to this page: Oded Breuer

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