What is it about?
Stem cells can help the surgical repair of cartilage defects. But, stem cells often prefer to attach to something. Here we examined how stem cells interact with a "micronized" cartilage powder. Does micronized cartilage support stem cell viability, attachment, and production of new cartilage matrix?
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Why is it important?
As many exciting new products become available for surgeons to use in the clinic to help patients, it is important to examine how these products interact with cells and with eachother. In this manuscript we highlighted the importance of first fully hydrating the micronized cartilage powder before mixing with cells. Once fully hydrated, the cartilage powder supported living cells. We observed nice integration of the cartilage powder with newly formed cartilage matrix made by the stem cells.
Perspectives
Great collaborative teamwork between medical students, surgeons, basic scientists, and biomedical engineers, highlighting the different perspectives of each and showing how unique questions can get asked and answered.
Professor Dominik R Haudenschild
Houston Methodist
Read the Original
This page is a summary of: Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus, Foot & Ankle Orthopaedics, September 2017, SAGE Publications,
DOI: 10.1177/2473011417s000055.
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