What is it about?
To increase the chance of finding bioactive small molecules that will be effective for the treatment of mucositis, a screen on primary gut organoid cultures has been conducted under conditions that mimic the disease in patients.
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Why is it important?
The findings reveal that a patho-physiological organoid model system is suitable for drug discovery.
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This page is a summary of: Screening of Intestinal Crypt Organoids, SLAS DISCOVERY, January 2017, SAGE Publications,
DOI: 10.1177/2472555216683651.
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