What is it about?
Using the principles of tissue engineering and regenerative medicine to regenerate alveolar bone in the place of tooth extraction via bio-glass material that have special characteristics to attract cells, enhance angiogenesis, differentiate mesenchymal stem cells into bone forming cells and create an environment that focus on functional regeneration and remodeling. The expected novel application in orthodontic class II may challenge using the material prior to orthodontic treatment that may may have an effect on growth, occlusion and function in these cases. The 1st phase of the study is published in this paper and the 2nd phase is currently going on.
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Why is it important?
It shed the light on two important ares in the clinical application of Dentistry 1- New mechanism in alveolar ridge preservation 2- New promising procedures of handling class II orthodontic cases children that may have long term and definitive effect
Perspectives
This work focus on multi and interdisciplinary aspect of the new science and technology of tissue engineering and regenerative medicine in its 2nd generation. At this generation we all look forward to attract cells for homing into the area that need and required regeneration not in the conventional way e.g just lay down bone but it using the principles of engineering in an artistic way of patterning the new bone to suit the function of the area of interest in the short term " 1st objective or ridge preservation ". In long term , we expect that it will affect the rate and mechanism of tooth movement and the growth occurred in the jaws that should influence the functional therapy of class II orthodontic cases
Professor Mona MK Marei
Faculty of dentistry-Alexandria Egypt
Read the Original
This page is a summary of: Bioglass in Alveolar Bone Regeneration in Orthodontic Patients, JDR Clinical & Translational Research, August 2016, SAGE Publications,
DOI: 10.1177/2380084416660672.
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