What is it about?
We studied whether taking an antioxidant called lipoic acid to treat optic neuritis ( optic nerve inflammation) protected the optic nerve in long term.
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Why is it important?
Optic nerve inflammation is a serious and potentially permanently disabling disease of the eye. There are currently no treatments for acute optic neuritis. Treatments targeting optic nerve protection are urgently needed.
Perspectives
The study while did not meet its enrollment goal did not show any hint of efficacy in the subjects who received the lipoic acid. Lipoic acid taken orally for 6 weeks after optic neuritis diagnosis is safe. Our study highlights unique challenges in studying a disease like acute optic neuritis where getting the subjects who meet the qualifying criteria in timely fashion for the study can be difficult.
VIJAYSHREE YADAV
Oregon Health and Science University Foundation
Read the Original
This page is a summary of: Oral lipoic acid as a treatment for acute optic neuritis: a blinded, placebo controlled randomized trial, Multiple Sclerosis Journal - Experimental Translational and Clinical, April 2019, SAGE Publications,
DOI: 10.1177/2055217319850193.
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