What is it about?

The current NICE guideline excluded women in the older age range where dementia is two to three times more common in females than males. With hindsight it might have been better to look at memory and minimal cognitive impairment as a topic, as well as dementia. Undoubtedly, there is good evi- dence that estrogen has an impact on memory, espe- cially short-term memory in menopausal women.

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Why is it important?

This area of cognitive functioning and the menopause is very exciting. My own feeling is that while we do not have the full picture, I have little doubt that estrogen will prove to be very important in pro- tecting cognitive function and alleviating the scourge of dementia.

Perspectives

My own feeling is that while we do not have the full picture, I have little doubt that estrogen will prove to be very important in pro- tecting cognitive function and alleviating the scourge of dementia.

Dr Anthony Michael Mander
Nuffield Healthcare

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This page is a summary of: Long-term benefits and risks of HRT (Section 11): Dementia, Post Reproductive Health, June 2016, SAGE Publications,
DOI: 10.1177/2053369116648254.
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