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Shows the outcome of 1000 operations on large prostates using Laser. It is successful and durable treatment of any sized enlarged prostate. Case Series Holmium laser enucleation of the prostate: A single-centre case series of 1000 patients Danielle Whiting, Branimir Penev, Katherine Guest Abstract Objective: To describe the short and long-term complications of over 1000 cases of Holmium laser enucleation of the prostate (HoLEP) in a single centre. Methods: A prospective database of all HoLEP procedures performed between December 2003 and March 2017 was analysed. Results: A total of 1016 HoLEP procedures were performed. Median patient age was 72 years (range 41–95). There was a significant improvement in urinary flow, post-void residual volume, IPSS and QoL score (p < 0.0001). Pre-operative acute urinary retention was present in 403 patients (39.7%). Post-operatively five patients (1.2%) continued with a long- term catheter. Early and late complications consisted of failed initial voiding trial (10.6%), stress incontinence (transient 6.5%; persistent 0.3%), frequency/dysuria (5.6%), urinary tract infection (5.3%), urethral stricture (4.8%), submeatal stenosis (1.9%), return to theatre (1.5%), bladder neck stenosis (1.3%), bleeding (1.2%), epididymitis (0.7%), confusion (0.3%), transurethral resection of the prostate conversion (0.2%), ureteric obstruction (0.2%), vomiting (0.2%), anuric renal failure (0.1%), chest infection (0.1%), chest pain (0.1%), myocardial infarction (0.1%), rectoprostatic fistula (0.1%), supraventricular tachycardia (0.1%) and urinary sepsis (0.1%). Five-year reoperation rate was 3.7%. Conclusion: HoLEP is a safe treatment for bladder outflow obstruction secondary to an enlarged prostate. It is associated with few early and late complications and has a low reoperation rate.

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Why is it important?

It is the most successful surgical treatment of enlarged prostate

Perspectives

I perform this surgery exclusively since 2010, already nearly 2000 cases to date. Very satisfactory outcomes

Branimir Penev
Royal College of Surgeons of England

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This page is a summary of: Holmium laser enucleation of the prostate: A single-centre case series of 1000 patients, Journal of Clinical Urology, July 2021, SAGE Publications,
DOI: 10.1177/20514158211033741.
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