What is it about?
During and immediately after joint replacement operations, bleeding from the surgical site is problematic. In a review of 163 joint replacement operations, preventive administration of a medicine called tranexamic acid diminished blood loss and significantly reduced the need for blood transfusions.
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Why is it important?
This "real-world" hospital experience confirms the beneficial effects of use of tranexamic acid on operative blood loss that previously was shown in controlled investigations of joint arthroplasty.
Perspectives
Because bleeding complications and resource utilization were diminished with use of tranexamic acid, this medication now is used routinely during joint replacement operations in our hospital.
Larry Golightly
University of Colorado Hospital
Read the Original
This page is a summary of: Perioperative blood loss in total hip and knee arthroplasty: Outcomes associated with intravenous tranexamic acid use in an academic medical center, SAGE Open Medicine, November 2016, SAGE Publications,
DOI: 10.1177/2050312116637024.
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