Dual control of pituitary thyroid stimulating hormone secretion by thyroxine and triiodothyronine in athyreotic patients

  • Rudolf Hoermann, John E. M. Midgley, Johannes W. Dietrich, Rolf Larisch
  • Therapeutic Advances in Endocrinology and Metabolism, June 2017, SAGE Publications
  • DOI: 10.1177/2042018817716401

What is it about?

TSH is subject to feedback regulation by thyroid hormones.

Why is it important?

This study examines the differential contributions of FT4 and FT3 in the feedback control of pituitary TSH.

Perspectives

Professor Rudolf Hoermann

Circulating FT3 levels impact on pituitary TSH, both directly and by interaction with FT4, suggesting cascade control of the regulation. Practical implications for LT4 treatment are discussed.

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http://dx.doi.org/10.1177/2042018817716401

The following have contributed to this page: Professor Rudolf Hoermann and PD Dr. med. Johannes W Dietrich