What is it about?
How do stem cells know whether to remain stem cells or start differentiating into other tissues? LRF is a factor that promotes stem cell expansion and can inhibit commitment to a cartilage phenotype.
Featured Image
Why is it important?
Much emphasis is on understanding how to make stem cells commit to a specific phenotype. Here we showed that LRF is a factor that helps create more stem cells and prevents their lineage commitment.
Read the Original
This page is a summary of: The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation, Cartilage, July 2013, SAGE Publications,
DOI: 10.1177/1947603513497570.
You can read the full text:
Contributors
The following have contributed to this page
