Transdermal oxybutynin for overactive bladder

What is it about?

Medication delivery through the skin via patches or gels has the purported advantage of avoiding metabolism in the liver which can result in reduced bioavailability and creation of side effect-inducing metabolites. This article reviews the data on transdermal delivery of the antimuscarinic medication oxybutynin.

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Why is it important?

We review the most up to date information regarding the mechanism of action, efficacy, cost, and availability of transdermal delivery systems for oxybutynin.