What is it about?
Excellent therapeutic response to bilogics reveals that the TNF/IL-23/IL-17 axis plays a crucial role in psoriasis. However, information on what kind of autoantigens induce the Th17 cell differentiation remain limited.
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Why is it important?
In this review article, we summarizes recent understandings on autoantigens which drives IL-17 production from T cells.
Perspectives
This review article help our understandings that psoriasis is a heterogenous autoimmune disease which mainly target the body surface, the skin.
Masutaka Furue
Department of Dermatology, Kyushu University
Read the Original
This page is a summary of: The contribution of IL-17 to the development of autoimmunity in psoriasis, Innate Immunity, May 2019, SAGE Publications,
DOI: 10.1177/1753425919852156.
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