What is it about?

chondrocyte mechanosensitive ion channels

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Why is it important?

provide a basis for further examination of mechanotransduction in cartilage and raise a possibility of therapeutically targeting Piezo2-mediated mechanotransduction for the treatment of cartilage disease induced by repetitive mechanical forces.

Perspectives

it is basis for investigating chondrocyte-PCM interaction in cell microenvironment

Quanyou Zhang
Taiyuan University of Technology

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This page is a summary of: Roles of TRPV4 and piezo channels in stretch-evoked Ca2+ response in chondrocytes, Experimental Biology and Medicine, December 2019, SAGE Publications,
DOI: 10.1177/1535370219892601.
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