What is it about?
Metabolic control is important in patients with diabetic retinopathy and diabetic macular edema. Previous studies have demonstrated that tight sugar control, for example, can reduce or prevent the progression of diabetic retinopathy. However, we observed that this is not always true in diabetic macular edema. This paper showed the different impact of sugar control in diabetic patients with and without macular edema.
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Why is it important?
The result in our study showed that glycosylated hemoglobin controlled at a relatively lower level did not benefit central macular thickness in the presence of macular edema. The role of sugar control under such circumstance should be further reexamined.
Perspectives
We presented the result somewhat contrary to popular belief, however, is of clinical significance. We as ophthalmologists may have a hard time treating patients with diabetic macular edema effectively even though a number of anti-VEGF injections were administered with patients on fairly good sugar control. Optimal control, rather than tight control of metabolic factors, probably has a significant impact on the treatment of diabetic macular edema.
mengju tsai
Read the Original
This page is a summary of: Impact of metabolic control on macular thickness in diabetic macular oedema, Diabetes and Vascular Disease Research, December 2017, SAGE Publications,
DOI: 10.1177/1479164117746023.
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