What is it about?
Two cases of NMO/NMOSD were presented in whom intractable cough was a feature of acute phase, irrespective of the presence of another typical symptom intractable hiccup. Intractable cough symptoms have been regarded as a sign of preceding infection, however, our cases indicate that the nucleus of the solitary tract located at the medulla oblongata near area postrema seems to be involved. Therefore, intractable cough may be an additional symptom typical of NMO/NMOSD.
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Why is it important?
Not only intractable hiccup but also intractable cough may be a clue to the diagnosis of NMO/NMOD.
Perspectives
Intractable cough as a neurological symptom of NMO/NMOSD may have been treated with antibiotics as it was thought to be due to preceding infection. However, as the present case report pointed out, this peculiar symptoms should be treated with intravenous high-dose corticosteroids.
Professor Makoto Matsui
Kanazawa Medical University
Read the Original
This page is a summary of: Intractable cough as characteristic symptom of neuromyelitis optica and neuromyelitis optica spectrum disorder, Multiple Sclerosis Journal, July 2015, SAGE Publications,
DOI: 10.1177/1352458515596602.
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