What is it about?
HGF/c-met axis plays a crucial role in thyroid cancer development. THis was for different cellular distributions of both ligands and receptors along in the thyroid sequence benign lesions vs malignant proliferations. Further HGF/c-met signals modulate mesenchymal tissue surrounding epithelial cancer cells.
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Why is it important?
We define HGF/c-met signals for determining their rules in personalized therapies of cancers.
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This page is a summary of: Hepatocyte Growth Factor/C-Met Axis in Thyroid Cancer: From Diagnostic Biomarker to Therapeutic Target, Biomarker Insights, January 2017, SAGE Publications,
DOI: 10.1177/1177271917701126.
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