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Why is it important?
There is good concordance between the formulas, with less than 10% of patients expected to receive a different initial dose of chemotherapy. The MDRD formula is a reasonable alternative to the CG formula for dosing of cancer drugs.
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This page is a summary of: Evaluation of creatinine-based formulas in dosing adjustment of cancer drugs other than carboplatin, Journal of Oncology Pharmacy Practice, July 2009, SAGE Publications,
DOI: 10.1177/1078155209337663.
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