What is it about?
This article provides new evidences on the long term beneficial effects of islet transplantation in patients affected by type 1 diabetes mellitus. The continuous glucose monitoring showed a proper glycemic control in islet recipients many years after the transplant with no need of exogenous insulin administration
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Why is it important?
This is the first study showing an overall improvement of glycemic variability in long-term insulin-independent patients after islet transplantation. This adds new data about the feasibility and the success of islet transplantation as a therapeutical option for selected patients affected by type 1 diabetes mellitus.
Perspectives
We used a continous glucose monitoring system to describe glucose control after transplantation. This should be proposed as a useful tool for the monitoring of islet function. In perspective this tool might be useful to monitor islet graft function and for the early detection of initial graft exaustion
Federico Bertuzzi
Niguarda Hospital, Milan, Italy
Read the Original
This page is a summary of: Long-term Effect of Islet Transplantation on Glycemic Variability, Cell Transplantation, May 2018, SAGE Publications,
DOI: 10.1177/0963689718763751.
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