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Why is it important?

There are unmet needs in the treatment of SLE. IL-23 blockade has some positive effects in the mice model of lupus nephritis.

Perspectives

SLE is used to be viewed as a B cell-mediated autoimmune disease. However, the success of rituximab in AAV in contrast to SLE implies that we have to rethink our hypothesis about the pathogenesis of SLE.

Dr Chien-Sheng Wu
Far Eastern Memorial Hospital

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This page is a summary of: Ustekinumab treatment in a patient with psoriasis and systemic lupus erythematosus, Lupus, November 2014, SAGE Publications,
DOI: 10.1177/0961203314561072.
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