What is it about?

There are many ays to approach the problem of over prescribing of antibiotics for acute RTIs, ranging from educational efforts to use of point-of-care laboratory tests. However, it has been unclear how these compare to each other, in which settings and for which patients. This review evaluates the evidence across all intervention types and incorporates evaluation of study quality, and consistency and precision of findings. We also considered whether the intervention had adverse consequences for the patient or the provider. A small number of interventions rose to the top using this rubric, although others show promise.

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Why is it important?

Improving the appropriateness of antibiotic prescribing for acute RTIs may help to stem the serious problem of antibiotic resistance. Health-plans and individual clinicians need to understand the pros and cons of applying the various methods of improving appropriateness of antibiotic prescribing for acute RTIs in order to choose specific interventions for specific situations. Some interventions require resources, while others do not. Understanding any potential adverse consequences, and whether these have even been studied is also important in understanding the best fit for their situation.

Perspectives

This report is complex, but brings the best methodology in systematic reviews to this area of research. Previously the evidence was reviewed in silos, divided mainly by categories of the type or mechanism of the intervention, did not consider any adverse consequences of the interventions, and did not consider the GRADE domains of risk of bias, directness, consistency, and precision to the evidence.

Marian McDonagh
Oregon Health & Science University

Read the Original

This page is a summary of: Interventions to reduce inappropriate prescribing of antibiotics for acute respiratory tract infections: summary and update of a systematic review, Journal of International Medical Research, July 2018, SAGE Publications,
DOI: 10.1177/0300060518782519.
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