What is it about?

1. The symptom prevalence of patients with end-stage liver disease resembled that of patients with other advanced conditions. 2. The most frequently reported symptoms were pain, breathlessness, muscle cramps, sleep disturbance, depression, anxiety, and erectile dysfunction. 3. Decompensation led to significant worsening of health-related quality of life.

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Why is it important?

End-stage liver disease is a common cause of morbidity and mortality worldwide, yet little is known about its symptomatology and impact on health-related quality of life.

Perspectives

Given the diversity of symptoms and significantly impaired health-related quality of life, multidisciplinary approach and timely intervention are crucial in the care of patients with end-stage liver disease.

Jen-Kuei Peng
King's College London

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This page is a summary of: Symptom prevalence and quality of life of patients with end-stage liver disease: A systematic review and meta-analysis, Palliative Medicine, October 2018, SAGE Publications,
DOI: 10.1177/0269216318807051.
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