What is it about?
Procainamide is a cardiac anti-arrhythmic drug that can be given intravenously. We studied the chemical stability and physical compatibility of the undiluted drug in glass vials or when diluted in normal saline and stored in PVC bags.
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Why is it important?
Long term stability under these conditions has never been determined and there is a incompatibility when diluted with dextrose solutions. Both solution were found to be stable for 193 days when stored at either 23 degrees C or 5 degrees C.
Perspectives
I hope this article will help other healthcare professionals who are looking for stability information regarding procainamide.
Ron Donnelly
Ottawa Hospital
Read the Original
This page is a summary of: Stability of Procainamide Injection in Clear Glass Vials and Polyvinyl Chloride Bags, Hospital Pharmacy, August 2017, SAGE Publications,
DOI: 10.1177/0018578717724896.
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