What is it about?
With an intuitive and practical perspective, this paper makes the adaptive clinical trial design easy to understand and implement. In fact, if one is asked to perform the adaptive clinical trial design without access to the pertinent papers, one can easily derive the key formula in a fairly short time. This method can apply to all sorts of endpoints and clinical settings. Simulation can be used to confirm its utility.
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Why is it important?
Adaptive clinical trial design made easy in a generalized fashion.
Read the Original
This page is a summary of: A Practical Perspective: Application of the Generalized Approach for Adaptive Design, Therapeutic Innovation & Regulatory Science, January 2019, SAGE Publications, DOI: 10.1177/2168479019825634.
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