What is it about?
Mitochondrial function is upregulated to produce more ATP in stem cell differentiation.
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Why is it important?
Metabolic reprogramming as the increase in respiration indicates the quality of stem cells.
Perspectives
Acetylation of mitochondrial proteins regulates mitochondrial function and antioxidant defense.
Professor and Director Yau-Huei Wei
Changhua Christian Hospital
Read the Original
This page is a summary of: Current understanding and future perspectives of the roles of sirtuins in the reprogramming and differentiation of pluripotent stem cells, Experimental Biology and Medicine, March 2018, SAGE Publications,
DOI: 10.1177/1535370218759636.
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