Thyroid cancer and HGF/cmet system
What is it about?
HGF/c-met axis plays a crucial role in thyroid cancer development. THis was for different cellular distributions of both ligands and receptors along in the thyroid sequence benign lesions vs malignant proliferations. Further HGF/c-met signals modulate mesenchymal tissue surrounding epithelial cancer cells.
Why is it important?
We define HGF/c-met signals for determining their rules in personalized therapies of cancers.
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