SOX2 gene and myopia

What is it about?

Although the SOX2 gene mutation could lead to severe phenotypes, it played an important role in eyeball development, which suggested that this gene was probably a candidate for ametropia.we selected SOX2 gene, screened three tag SNPs for sequencing analysis, trying to find out high myopia-related loci to explore the association between SOX2 gene and high myopia.

Featured Image

Photo by Curology on Unsplash

Photo by Curology on Unsplash

Why is it important?

In Chinese population, rs4575941 in SOX2 gene was likely to play some roles in the genetic susceptibility to high myopia, the rs4575941 allele G might be a risk gene for high myopia.