What is it about?

The first case report of peripheral primitive neuroectodermal tumor (PNET) in Formosan serow with confirmation by histopathology and immunohistochemical stains.

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Why is it important?

Gain more knowledge on wildlife diseases and parthenogenesis on neoplasia.

Perspectives

PNETs with FLI-1 expression have not been reported in any animal species, to our knowledge, and thus the tumorigenesis and the use of FLI-1 as a biomarker for diagnosis or therapy is poorly studied. I hope this study can inspire further investigations of cytogenetics (such as the chromosomal translocation of t(11; 22)(q24;q12) in humans) by fluorescence in situ hybridization and/or reverse-transcription PCR in animals with PNET or other common neoplasms are necessary to determine the role of FLI-1 in tumorigenesis and the use of FLI-1 as a marker in animals.

Dr. Wen-Ta Li
Fishhead Labs LLC

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This page is a summary of: Retroperitoneal extraosseous peripheral primitive neuroectodermal tumor in a Formosan serow: case report and literature review, Journal of Veterinary Diagnostic Investigation, October 2019, SAGE Publications, DOI: 10.1177/1040638719879198.
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