What is it about?
Association of Dopamine β-hydroxylase genetic variants with cognition and Tardive dyskinesia in Schizophrenia subjects.
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Why is it important?
Inter individual genetic variant profile differences in Dopamine β-hydroxylase may contribute to the propensity or severity of Tardive dyskinesia and cognitive symptoms in Schizophrenia subjects. Knowing the variant profile may help to tailor inhibitors according to the variant profile of the individual leading to personalized medicine.
Perspectives
This may draw attention of groups working on psychiatric diseases and who could attempt to replicate the findings that could help ameliorating side effects of anti psychotics.
Dr. Toyanji Joseph Punchaichira
University of Delhi
Read the Original
This page is a summary of: Association of regulatory variants of dopamine β-hydroxylase with cognition and tardive dyskinesia in schizophrenia subjects, Journal of Psychopharmacology, January 2020, SAGE Publications,
DOI: 10.1177/0269881119895539.
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