What is it about?
Chronic rhinosinusitis (CRS) is one of the most common inflammations in the upper airway. Despite the wide prevalence of CRS, the pathogenesis of this disease is poorly understood. Several components of the innate immune system may play a significant role in CRS, including Toll-like receptor 4 (TLR4), TLR9, and high-mobility group box 1 protein (HMGB1). This study was conducted to determine the expression of TLR4, TLR9, HMGB1, and pNFk-B p65 in paraffin-embedded blocks of patients with CRS with nasal polyps compared with those of the control group.
Featured Image
Why is it important?
This study was conducted to determine the expression of TLR4, TLR9, HMGB1, and pNFk-B p65 in paraffin-embedded blocks of patients with CRS with nasal polyps compared with those of the control group.
Perspectives
Chronic rhinosinusitis (CRS) is one of the most common inflammations in the upper airway. Despite the wide prevalence of CRS, the pathogenesis of this disease is poorly understood. Several components of the innate immune system may play a significant role in CRS, including Toll-like receptor 4 (TLR4), TLR9, and high-mobility group box 1 protein (HMGB1). This study was conducted to determine the expression of TLR4, TLR9, HMGB1, and pNFk-B p65 in paraffin-embedded blocks of patients with CRS with nasal polyps compared with those of the control group.
Homa Davoodi
Cancer Research Center, Golestan University of Medical Sciences
Read the Original
This page is a summary of: Correlation Between HMGB1 and TLR4 Expression in Sinonasal Mucosa in Patients With Chronic Rhinosinusitis, Ear Nose & Throat Journal, June 2019, SAGE Publications,
DOI: 10.1177/0145561319858915.
You can read the full text:
Contributors
The following have contributed to this page
