What is it about?
Recent researches have clarified the relationship between gastroesophageal reflux and sleep bruxism. This paper aimed to assess the efficacy of a proton pump inhibitor on sleep bruxism. The administration of a proton pump inhibitor significantly reduced the frequencies of bruxism episodes.
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Why is it important?
Our findings show that the significant reduction of bruxism episodes by administration of proton pump inhibitor. Gastrointestinal symptoms were also frequently observed in patients with sleep bruxism.
Perspectives
This study partly corresponds to the phase IIA trial, and the results of the present study may serve as a proof of concept for the applicability of pharmacological gastroesophageal reflux disease treatment for sleep bruxism patients. In the future, a low-cost, large-scale research study, corresponding to a phase IIB or III trial must be employed to examine the different types and doses of proton pump inhibitors and to determine the discriminating factors of sleep bruxism patients for whom pharmacological therapy is successful.
Haruhito Omure
Kagoshima Daigaku
Read the Original
This page is a summary of: Evaluation of a Proton Pump Inhibitor for Sleep Bruxism, Journal of Dental Research, July 2016, SAGE Publications,
DOI: 10.1177/0022034516662245.
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