Schizophrenia Beyond Genome-Wide Association Studies: It’s About Time

What is it about?

Genetic research about schizophrenia has uncoverd literally hundreds of potential genes that increase risk but how individuals become ill is not obvious from these results. In this overview, we focus on how genes work together in biological systems to account for risk and how these systems critical change during development. The interaction of the systems biology related to genetic risk and the developmental trajectory spanning the first two decdes of life offers insights into how schizophrenia develops and varies between individuals.

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