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A recent study in the Journal found a lower risk of schizophrenia 10 years after use of doxycycline compared to use of other antibiotics. I note that one possible mediator of this relationship could be the antiparasitic effect of doxycycline on Toxoplasma gondii, which has been proposed as a cause of some fraction of schizophrenia cases.
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This page is a summary of: Doxycycline, Schizophrenia, and Toxoplasmosis, American Journal of Psychiatry, May 2026, American Psychiatric Association,
DOI: 10.1176/appi.ajp.20251231.
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