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We examined the link between cannabis use disorder and mental health conditions as compared to other substance use disorders using a retrospective cohort design. Our results showed that adults with cannabis use disorder had a lower risk of developing most mental health conditions in adults but a higher risk for many conditions in children. There may be age-dependent effects of cannabis on the development of mental health conditions.

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This page is a summary of: Association of Cannabis Use Disorder Versus Other Substance Use Disorders With Psychiatric Conditions: A Propensity-Matched Retrospective Cohort Analysis, American Journal of Psychiatry, April 2026, American Psychiatric Association,
DOI: 10.1176/appi.ajp.20250336.
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