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Depressive symptoms are common in Schizophrenia Spectrum Disorders (SSDs), yet poorly understood. Conceptual similarities between depressive and negative symptoms add complexity to the process of developing biomarkers and treatment interventions. In this study, a data-driven methodology was used to elucidate the brain circuitry that underlies both depressive and negative symptoms in SSDs.

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This page is a summary of: Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders, American Journal of Psychiatry, October 2024, American Psychiatric Association,
DOI: 10.1176/appi.ajp.20230655.
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