What is it about?
Subjects with psychotic disorders have a reduction in fast brain waves called "gamma-band oscillations" important for communication. However, it is not clear if this impairment emerges over the course of the disease or even before the onset of psychotic symptoms. Our results for the first time suggest that in individuals at genetic risk for psychosis gamma band oscillations do not increase from childhood to adulthood as expected in typically developing individuals.
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Why is it important?
Our findings highlight the importance of understanding psychotic disorders in terms of abnormal brain development to guide targeted preventive intervention.
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This page is a summary of: Aberrant Developmental Patterns of Gamma-Band Response and Long-Range Communication Disruption in Youths With 22q11.2 Deletion Syndrome, American Journal of Psychiatry, March 2022, American Psychiatric Association, DOI: 10.1176/appi.ajp.2021.21020190.
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