What is it about?
Pterygium is a fibrovascular disease without known pathogenetic mechanism. SPARC Is a matrix protein that is upregulated in this disease. There may be remodeling of the ocular surface tissue, which is dependent on enzymes such as matrix metalloproteinases. This article explain the possible disturbances in these molecular systems.
Featured Image
Photo by National Cancer Institute on Unsplash
Why is it important?
It may be possible to treat early pteryigum by interfering with these pathways.
Perspectives
SPARC proteins affects basement membrane in pterygium
Prof Louis Tong
National University of Singapore
Read the Original
This page is a summary of: Involvement of SPARC and MMP-3 in the Pathogenesis of Human Pterygium, Investigative Ophthalmology & Visual Science, February 2012, Association for Research in Vision and Ophthalmology (ARVO),
DOI: 10.1167/iovs.11-7941.
You can read the full text:
Contributors
The following have contributed to this page
