Hybrid Macroporous Gelatin/Bioactive-Glass/Nanosilver Scaffolds with Controlled Degradation Behavior and Antimicrobial Activity for Bone Tissue Engineering

  • M. Yazdimamaghani, D. Vashaee, S. Assefa, K .J. Walker, S. V. Madihally, G .A. Köhler, L. Tayebi
  • Journal of Biomedical Nanotechnology, June 2014, American Scientific Publishers
  • DOI: 10.1166/jbn.2014.1783

Antimicrobial gelatin/bioactive-glass/nanosilver scaffolds for bone tissue engineering

What is it about?

Silver nanoparticles were successfully synthesized in situ in gelatin solution by heat treatment reduction as a simple and "green" method in which gelatin acted as a natural reducing and stabilizing agent. The in vitro viability of human mesenchymal stem cells (hMSC) and the antibacterial activity against gram-negative Escherichia coli and gram-positive Staphylococcus aureus were tested on the scaffolds.

Why is it important?

A new composition of gelatin/bioactive-glass/silver nanoparticle was synthesized and employed to prepare antibacterial macroporous scaffolds with potential applications in bone tissue engineering.

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The following have contributed to this page: Mr Mostafa Yazdimamaghani and Dr Sundararajan V Madihally