MultiOMICs of WTC-Particulate Induced Persistent Airway Hyperreactivity: Role of Receptor for Advanced Glycation End Products

What is it about?

RAGE mediates lung disease that can occur one month after a single, high-intensity exposure to World Trade Center particulate matter. Lack of RAGE could limit the extent of cellular injury, inflammation, and remodeling in a mouse model. Further work is needed to investigate how lack of RAGE can decrease lung injury and inflammation.

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